Cardiac-specific overexpression of HIF-1α during acute myocardial infarction ameliorates cardiomyocyte apoptosis via differential regulation of hypoxia-inducible pro-apoptotic and anti-oxidative genes
Ratul Datta Chaudhuri, Anirban Banik, Biswajit Mandal, Sagartirtha Sarkar
Topics & Concepts
Downregulation and upregulationChromatin immunoprecipitationApoptosisCell biologyRepressorHypoxia (environmental)BiologyTranscription factorPromoterMolecular biologyGeneCancer researchChemistryGene expressionBiochemistryOxygenOrganic chemistryCancer, Hypoxia, and MetabolismNF-κB Signaling PathwaysCell death mechanisms and regulation