Biomarkers and short-term prognosis in COVID-19
Óscar M. Peiró, Anna Carrasquer, Raúl Sánchez-Giménez, Nisha Lal-Trehan, Víctor Del-Moral-Ronda, Gil Bonet, Isabel Fort-Gallifa, Ester Picó-Plana, Natalia Bastón-Paz, Cristina Gutiérrez, Alfredo Bardajı́
Abstract
PURPOSE: The aim of our study was to analyse the short-term prognostic value of different biomarkers in patients with COVID-19. METHODS: We included patients admitted to emergency department with COVID-19 and available concentrations of cardiac troponin I (cTnI), D-dimer, C-reactive protein (CRP) and lactate dehydrogenase (LDH). Patients were classified for each biomarker into two groups (low vs. high concentrations) according to their best cut-off point, and 30-day all-cause death was evaluated. RESULTS: = 0.115). CONCLUSIONS: In patients with COVID-19, increased concentrations of cTnI, D-dimer, CRP and LDH are associated with short-term mortality. Of these, cTnI provides better mortality risk prediction. However, differences with D-dimer were non-significant.