A CRISPR/Cas12 trans-cleavage reporter enabling label-free colorimetric detection of SARS-CoV-2 and its variants
Hansol Kim, Hyowon Jang, Jayeon Song, Sang Mo Lee, Seoyoung Lee, Hyung‐Jun Kwon, Sun‐Joo Kim, Taejoon Kang, Hyun Gyu Park
Topics & Concepts
AmpliconCRISPRLoop-mediated isothermal amplificationRecombinase Polymerase AmplificationMolecular diagnosticsComputational biologyMolecular biologyChemistryPolymerase chain reactionBiologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Combinatorial chemistryDNAGeneticsCoronavirus disease 2019 (COVID-19)GeneMedicineInfectious disease (medical specialty)DiseasePathologyCRISPR and Genetic EngineeringAdvanced biosensing and bioanalysis techniquesBiosensors and Analytical Detection