Modulation of Natural HLA-B*27:05 Ligandome by Ankylosing Spondylitis-associated Endoplasmic Reticulum Aminopeptidase 2 (ERAP2)
Elena Lorente, Miguel Gomez Fontela, Eilon Barnea, Antonio J. Martín-Galiano, Carmen Mir, Begoña Galocha, Arie Admon, Pilar Lauzurica, Daniel López
Abstract
These findings highlight the pathogenic role of this aminopeptidase in the triggering of AS autoimmune disease.
Topics & Concepts
Endoplasmic reticulumAminopeptidaseBiologyHLA-B27SpondyloarthropathyHuman leukocyte antigenPeptideMolecular biologyBiochemistryAntigenAmino acidImmunologyArthritisLeucineSpondyloarthritis Studies and TreatmentsAutoimmune Bullous Skin DiseasesRheumatoid Arthritis Research and Therapies