Construction of glutathione-responsive paclitaxel prodrug nanoparticles for image-guided targeted delivery and breast cancer therapy
W Ma, Qiufeng Zhao, Shilong Zhu, Xinyue Wang, Chuangchuang Zhang, Daming Ma, Na Li, Yanyan Yin
Abstract
experimental. Overall, the HA/TPE-CS-SS-PTX NPs we constructed have excellent bio-imaging capabilities and can be served as a potential nanomedicine for PTX delivery against breast cancer.
Topics & Concepts
ProdrugPaclitaxelGlutathioneBreast cancerChemistryNanoparticlePharmacologyCancer researchCancerMedicineNanotechnologyMaterials scienceInternal medicineBiochemistryEnzymeLuminescence and Fluorescent MaterialsNanoplatforms for cancer theranosticsDendrimers and Hyperbranched Polymers