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Immobilized acyl-transfer molecular reactors enable the solid-phase synthesis of sterically hindered peptides

Siyuan Wei, Xuchun Zhang, Xiaoliang Yang, Fa Liu, Zhu‐Jun Yao

2025Nature Chemistry11 citationsDOI

Topics & Concepts

ChemistrySteric effectsSolid-phase synthesisCombinatorial chemistryPhase (matter)Organic chemistryBiochemistryPeptideChemical Synthesis and AnalysisPeptidase Inhibition and AnalysisAntimicrobial Peptides and Activities
Immobilized acyl-transfer molecular reactors enable the solid-phase synthesis of sterically hindered peptides | Litcius