Improving solubility and intrinsic dissolution rate of ofloxacin API through salt formation via mechanochemical synthesis with diphenic acid
Ajay Suresh, Shivani Gonde, Pradip Kumar Mondal, Jagabandhu Sahoo, Deepak Chopra
Topics & Concepts
ChemistryDissolutionCocrystalSolubilitySalt (chemistry)Differential scanning calorimetryAqueous solutionOfloxacinBioavailabilityInorganic chemistryNuclear chemistryHydrogen bondOrganic chemistryMoleculeBioinformaticsCiprofloxacinThermodynamicsBiochemistryAntibioticsPhysicsBiologyCrystallography and molecular interactionsCrystallization and Solubility StudiesEnzyme Structure and Function