Natural polymorphism of Ym1 regulates pneumonitis through alternative activation of macrophages
Wenhua Zhu, Erik Lönnblom, Michael Förster, Martina Johannesson, Pei Tao, Liesu Meng, Shemin Lu, Rikard Holmdahl
Abstract
-deficient macrophages contributed to cellular polarization. In conclusion, the natural polymorphism of Ym1 regulates alternative activation of macrophages associated with pulmonary inflammation.
Topics & Concepts
PneumonitisImmunologyPolymorphism (computer science)BiologyMedicineGeneticsGenotypeLungInternal medicineGeneStudies on Chitinases and ChitosanasesAntimicrobial Peptides and ActivitiesInvertebrate Immune Response Mechanisms