β-Escin reduces cancer progression in aggressive MDA-MB-231 cells by inhibiting glutamine metabolism through downregulation of c-myc oncogene
Sakine Akar, Hamiyet Dönmez‐Altuntaş, Zühal Hamurcu
Topics & Concepts
GlutamineGlutaminaseOncogeneCancer cellCancer researchDownregulation and upregulationGlutaminolysisApoptosisChemistryWestern blotCellCell growthViability assayCancerBiologyBiochemistryAmino acidCell cycleGeneGeneticsGlycosylation and Glycoproteins ResearchCancer, Hypoxia, and MetabolismPeptidase Inhibition and Analysis