Phytochemical investigation, anti-inflammatory, antipyretic and antinociceptive activities of Zanthoxylum armatum DC extracts-in vivo and in vitro experiments
Fiaz Alam, Kinza Mohammad Din, Rukhba Rasheed, Abdul Sadiq, Muhammad Saeed Jan, Amber Mehmood Minhas, Arif‐ullah Khan
Abstract
values for 15 and 69 against COX and 21 and 62 μg/ml against LOX. This study rationalize the usage of this spice in traditional medicine for management of pain and inflammation involving LOX and COX inhibition as possible mechanism. GC-MS analysis revealed the presence of various constituents which might contributed towards the pain and inflammation alleviation.
Topics & Concepts
PhytochemicalTraditional medicineAntipyreticBark (sound)In vivoNociceptionZanthoxylumAnti-inflammatoryPhytotherapyPharmacognosyPharmacologyChemistryIn vitroMedicineAnalgesicBiological activityBiologyBiochemistryReceptorBiotechnologyPathologyEcologyAlternative medicinePharmacological Effects of Natural CompoundsNatural product bioactivities and synthesisPhytochemistry and Biological Activities