Chlorpyrifos induces placental oxidative stress and barrier dysfunction by inducing mitochondrial apoptosis through the ERK/MAPK signaling pathway: In vitro and in vivo studies
Jun Bai, Siwei Deng, Huiyang Fu, Qing Yang, Fazheng Ren, Shenming Zeng, Zhaohui Chen, Ying Yang, Zhenlong Wu
Topics & Concepts
ApoptosisOxidative stressMAPK/ERK pathwayReactive oxygen speciesPlacentaCell biologyBiologyMitochondrionAndrologyIn vivoViability assaySignal transductionChemistryPharmacologyFetusEndocrinologyBiochemistryPregnancyMedicineGeneticsPesticide Exposure and ToxicityGlutathione Transferases and PolymorphismsEnvironmental Toxicology and Ecotoxicology