Autoinhibitory structure of preligand association state implicates a new strategy to attain effective DR5 receptor activation
Gang Du, Linlin Zhao, Yumei Zheng, Anissa Belfetmi, Tiantian Cai, Boying Xu, Karen Heyninck, Kim Van Den Heede, Marie-Ange Buyse, Pietro Fontana, Michael Bowman, Lih‐Ling Lin, Hao Wu, James J. Chou
Topics & Concepts
ReceptorEctodomainCell biologyTumor necrosis factor alphaSignal transductionBiologyImmunologyBiochemistryCell death mechanisms and regulationImmune Response and InflammationToxin Mechanisms and Immunotoxins