Human thymic T cell repertoire is imprinted with strong convergence to shared sequences
Nelli Heikkilä, Reetta Vanhanen, Dawit A. Yohannes, Iivari Kleino, Ilkka Mattila, Jari Saramäki, T. Petteri Arstila
Topics & Concepts
T-cell receptorRepertoireBiologyGeneticsLocus (genetics)GeneNegative selectionPositive selectionGene rearrangementT cellImmune systemGenomePhysicsAcousticsT-cell and B-cell ImmunologyMonoclonal and Polyclonal Antibodies ResearchImmune Cell Function and Interaction