A Novel Synthesis of Halogenated <i>gem</i>-Diboron Reagents
Tongchang Fang, Liangxuan Xu, Yucheng Qin, Nanquan Jiang, Chao Liu
Abstract
A novel synthesis of halogenated gem-diboronates (X-CR(Bpin)2) was developed.The reagents are stable and easy to prepare in a large scale.Tetra-substituted halogenated gem-diboronates can be prepared in high yields when using alkylsubstituted gem-dihalides, providing a new strategy for the synthesis of new gem-diboron compounds.
Topics & Concepts
ChemistryReagentCombinatorial chemistryOrganic chemistryOrganoboron and organosilicon chemistryCatalytic Cross-Coupling ReactionsChemical Synthesis and Analysis