Correlation of anti-tumour drug resistance with epigenetic regulation
Takuma Hayashi, Ikuo Konishi
Abstract
During treatment, the development of drug-resistant tumours remains an important challenge in cancer treatment. Epigenetic changes have been reported as one of the mechanisms for anti-tumour drug resistance. In clinical practice, a combination of epigenetic-related drugs can be considered as a future selection of cancer therapeutic drugs.
Topics & Concepts
EpigeneticsDrug resistanceDrugMedicineCancer drugsCancerBioinformaticsBiologyOncologyPharmacologyInternal medicineGeneticsGeneHistone Deacetylase Inhibitors ResearchProtein Degradation and InhibitorsEpigenetics and DNA Methylation