Litcius/Paper detail

Nano‐hydroxyapatite reinforced polylactic acid bioabsorbable cancellous screws for bone fracture fixations

Arbind Prasad, Siddharth Mohan Bhasney, Varatharajan Prasannavenkadesan, Mamilla Ravi Sankar, Vimal Katiyar

2023Journal of Applied Polymer Science21 citationsDOIOpen Access PDF

Abstract

Abstract Bioabsorbable polymer implants aid the fracture treatment to overcome the limitations of metallic implants like stress shielding, corrosion, and revision surgeries. The cancellous screw is one of the internal fixation implants more frequently used in fixation procedures. In this work, nano‐hydroxyapatite (nHAp) reinforced polylactic acid cancellous screws were developed for bone fracture treatment. The biocompatibility and mechanical tests were performed before and after in‐vitro hydrolytic degradation studies. The addition of nanofillers (10 wt% nHAp) enhanced the pullout strength, torsional strength, and shear strength by 18%, 48%, and 5%, respectively. The performed thermal studies confirmed that the nanohydroxyapatite facilitates the crystallization process. A mass loss of about 18% in the case of neat PLA and 12% in the case of 10 wt% nHAp was observed for 90 days of in‐vitro hydrolytic degradation studies. So, the developed combination of biocomposite could help fabricate patient‐specific bioabsorbable fixation devices like screws and plates.

Topics & Concepts

Polylactic acidMaterials scienceCancellous boneBiocompatibilityBiocompositeComposite materialArtificial boneStress shieldingBiomedical engineeringPolymerImplantSurgeryMedicineComposite numberMetallurgyBone Tissue Engineering MaterialsOrthopaedic implants and arthroplastyBone fractures and treatments
Nano‐hydroxyapatite reinforced polylactic acid bioabsorbable cancellous screws for bone fracture fixations | Litcius