Identification of nonmonotonic concentration-responses in Tox21 high-throughput screening estrogen receptor assays
Zhenzhen Shi, Menghang Xia, Shuo Xiao, Qiang Zhang
Topics & Concepts
Estrogen receptorReceptorHigh-throughput screeningIn vitro toxicologyIn vivoAgonistBiologyComputational biologyChemistryIn vitroInternal medicinePharmacologyBioinformaticsBiochemistryMedicineGeneticsBreast cancerCancerEffects and risks of endocrine disrupting chemicalsEstrogen and related hormone effectsComputational Drug Discovery Methods