A proof-of-concept study of maternal immune activation mediated induction of Toll-like receptor (TLR) and inflammasome pathways leading to neuroprogressive changes and schizophrenia-like behaviours in offspring
Pinku Mani Talukdar, Fazal Abdul, Michaël Maes, Michael Berk, Ganesan Venkatasubramanian, Bindu M. Kutty, Monojit Debnath
Topics & Concepts
OffspringPrepulse inhibitionInflammasomeTLR4Schizophrenia (object-oriented programming)TLR3Innate immune systemReceptorImmune systemImmunologyHippocampusInflammationEndocrinologyInternal medicineMedicinePregnancyBiologyToll-like receptorPsychiatryGeneticsTryptophan and brain disordersStress Responses and CortisolNeuroendocrine regulation and behavior