Oxidative stress and ferroptosis in diabetic cardiomyopathy: mechanistic interplay and therapeutic implications
Shan Li, Yuhe Shu, Shuyu Yang, Simin Zhang, Haoling Chen, Dan Wu, Bo Li, Li Dong
Topics & Concepts
Oxidative stressReactive oxygen speciesDiabetic cardiomyopathyDiabetes mellitusPathogenesisMechanism (biology)Cell biologyProgrammed cell deathLimitingMedicineCardiomyopathyOxidative phosphorylationMitochondrionGPX4ApoptosisDownregulation and upregulationAntioxidantPharmacologyCancer researchPathologicalBioinformaticsTherapeutic approachCellSignal transductionChemistryOxidative damageBiologyCause of deathPhenotypeInflammationFerroptosis and cancer prognosisCircular RNAs in diseasesGDF15 and Related Biomarkers