Hsp27, Hsp60, Hsp70, or Hsp90 depletion enhances the antitumor effects of resveratrol via oxidative and ER stress response in human glioblastoma cells
Evren Önay Uçar, Aslıhan Şengelen, Elif Mertoğlu Kamalı
Topics & Concepts
Unfolded protein responseGliomaOxidative stressHeat shock proteinTransfectionHsp70Cancer researchResveratrolHsp27Clonogenic assayApoptosisHSP60Viability assayTemozolomideBiologySmall interfering RNAEndoplasmic reticulumReactive oxygen speciesAutophagyHsp90 inhibitorHsp90Cell biologyCell culturePharmacologyBiochemistryGeneGeneticsHeat shock proteins researchSirtuins and Resveratrol in MedicineEndoplasmic Reticulum Stress and Disease