Is there a role for herpes simplex virus type 1 in multiple sclerosis?
Luisa F. Duarte, Sebastián Gatica, Almendra Castillo, Alexis M. Kalergis, Susan M. Bueno, Claudia A. Riedel, Pablo A. González
Abstract
Numerous studies relate the onset and severity of multiple sclerosis (MS) with viral infections. Herpes simplex virus type 1 (HSV-1), which is neurotropic and highly prevalent in the brain of healthy individuals, has been proposed to relate to MS. Here, we review and discuss the reported connections between HSV-1 and MS.
Topics & Concepts
Multiple sclerosisHerpes simplex virusBiologyVirologyHerpesviridaeVirusNeurotropic virusAlphaherpesvirinaeImmunologySimplexvirusViral diseaseMultiple Sclerosis Research StudiesHerpesvirus Infections and TreatmentsPeripheral Neuropathies and Disorders