Growth or death? Control of cell destiny by mTOR and autophagy pathways
Mahmoud Khalil, Mohamad Moustafa Ali, Jasmine Holail, Marwa Houssein
Topics & Concepts
AutophagyPI3K/AKT/mTOR pathwaymTORC2mTORC1Cell biologyMechanistic target of rapamycinRPTORProgrammed cell deathBiologyULK1Cell growthAutophagosomeLysosomeSignal transductionApoptosisKinaseProtein kinase ABiochemistryAMPKEnzymeAutophagy in Disease and TherapyPI3K/AKT/mTOR signaling in cancerPolyamine Metabolism and Applications