Litcius/Paper detail

Zirconium-catalyzed asymmetric Kabachnik–Fields reactions of aromatic and aliphatic aldehydes

Yijing Dai, Zheng Li, Debarshi Chakraborty, Babak Borhan, William D. Wulff

2021Chemical Science15 citationsDOIOpen Access PDF

Abstract

An effective catalyst has been developed for the three-component reaction of aldehydes, anilines and phosphites in an asymmetric catalytic Kabachnik–Fields reaction to give α-aminophosphonates.

Topics & Concepts

ChemistryCatalysisZirconiumComponent (thermodynamics)Organic chemistryPhysicsThermodynamicsOrganophosphorus compounds synthesisAsymmetric Hydrogenation and CatalysisChemical Synthesis and Analysis