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Anti-Neutrophilic Cytoplasmic Antibody (ANCA) Vasculitis Presented as Pulmonary Hemorrhage in a Positive COVID-19 Patient: A Case Report

Albadr Hussein, Khaled AL Khalil, Yasser Bawazir

2020Cureus37 citationsDOIOpen Access PDF

Abstract

Granulomatosis with polyangiitis is a small vessel vasculitis with a wide spectrum of presentation, ranging from limited disease to life-threatening situation such as alveolar hemorrhage. Immunosuppression is the corner stone of the treatment and if left untreated, the death toll increases dramatically. We presented a case of granulomatosis with polyangiitis, presented with alveolar hemorrhage associated with COVID-19 infection. The patient admitted to the intensive care unit, received pulse steroids, plasmapheresis and intravenous immunoglobulin. She was not given further immunosuppression because of the coexisting COVID-19. Up to our knowledge, this is the first reported case of alveolar hemorrhage secondary to granulomatosis with polyangiitis coexisting with COVID-19 infection.

Topics & Concepts

MedicineGranulomatosis with polyangiitisImmunosuppressionDiffuse alveolar hemorrhagePlasmapheresisPulmonary hemorrhageVasculitisPathologyImmunologyInternal medicineAntibodyLungDiseaseVasculitis and related conditionsInflammasome and immune disordersSarcoidosis and Beryllium Toxicity Research
Anti-Neutrophilic Cytoplasmic Antibody (ANCA) Vasculitis Presented as Pulmonary Hemorrhage in a Positive COVID-19 Patient: A Case Report | Litcius