Therapeutic Targeting of MYC in Head and Neck Squamous Cell Carcinoma
Shuo Liu, Zhen Qin, Yaqing Mao, Wenbo Zhang, Yujia Wang, Lingfei Jia, Xin Peng
Abstract
T cell in HNSCC correlated with poor prognosis. These results suggested the potential of small-molecule MYC inhibitors as anti-cancer therapeutic agents in HNSCC.
Topics & Concepts
Cancer researchHead and neck squamous-cell carcinomaCD8CarcinogenesisCellImmunotherapyMedicineHead and neck cancerCell growthCell cultureT cellCancerImmune systemBiologyImmunologyInternal medicineGeneticsinterferon and immune responsesUbiquitin and proteasome pathwaysProtein Degradation and Inhibitors