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Systematic Analysis of the Lysine Crotonylome and Multiple Posttranslational Modification Analysis (Acetylation, Succinylation, and Crotonylation) in Candida albicans

Xiaowei Zhou, Nana Song, Dongmei Li, Xiaofang Li, Weida Liu

2021mSystems27 citationsDOIOpen Access PDF

Abstract

C. albicans is a kind of pathogen of fungal infections that is found worldwide. Lysine crotonylation of proteins as a recently discovered PTM (posttranslational modification) may have a critical role in regulating cells.

Topics & Concepts

SuccinylationLysineCandida albicansAcetylationPosttranslational modificationFungal pathogenChemistryBiochemistryPathogenMicrobiologyBiologyEnzymeAmino acidGeneSirtuins and Resveratrol in MedicinePeptidase Inhibition and AnalysisAntifungal resistance and susceptibility