Litcius/Paper detail

Combined thioredoxin reductase and glutaminase inhibition exerts synergistic anti-tumor activity in MYC-high high-grade serous ovarian carcinoma

Prahlad V. Raninga, Yaowu He, Keshava K. Datta, Xue Lu, Uma R. Maheshwari, Pooja Venkat, Chelsea Mayoh, Harsha Gowda, Murugan Kalimutho, John D. Hooper, Kum Kum Khanna

2022Molecular Therapy33 citationsDOIOpen Access PDF

Topics & Concepts

Ovarian carcinomaSerous fluidCancer researchGlutaminaseThioredoxin reductaseThioredoxinEnzymeBiologySerous carcinomaChemistryOvarian cancerInternal medicineMedicineBiochemistryCancerGlutamineAmino acidRedox biology and oxidative stressCancer, Hypoxia, and MetabolismEndoplasmic Reticulum Stress and Disease