Chain-shattering polymeric sulfur dioxide prodrug micelles for redox-triggered gas therapy of osteosarcoma
Peng Liu, Weifei Zhang, Jiapeng Deng, Yien Zheng, Jian Weng, Fei Yu, Deli Wang, Ming Zheng, Bin Kang, Hui Zeng
Abstract
A chain-shattering polymeric SO 2 prodrug micelle system was fabricated for effective SO 2 delivery and redox-triggered SO 2 based gas therapy of osteosarcoma.
Topics & Concepts
MicelleProdrugRedoxOsteosarcomaMaterials scienceChain (unit)Combinatorial chemistryChemistryChemical engineeringOrganic chemistryCancer researchMedicineBiochemistryAstronomyAqueous solutionPhysicsEngineeringNanoplatforms for cancer theranosticsCancer, Hypoxia, and MetabolismSulfur Compounds in Biology