Induced fit activity-based sensing: a mechanistic study of pyrophosphate detection with a “flexible” Fe-salen complex
Prerna Yadav, Olivier Blacque, Andreas Roodt, Felix Zelder
Abstract
A detailed mechanistic study of pyrophosphate (PPi) detection with a fluorometric Fe-salen based probe unravels the key structural switch of the Fe-bound PPi (“induced fit principle”) explaining the novel selectivity over other competing analytes.
Topics & Concepts
PyrophosphateAnalyteSelectivityChemistryCombinatorial chemistryChromatographyBiochemistryCatalysisEnzymeMolecular Sensors and Ion DetectionMetal complexes synthesis and propertiesElectrochemical Analysis and Applications