A systematic review and meta-analysis of observational studies on the effects of epigenetic factors on serum triglycerides
Sadegh Mazaheri‐Tehrani, Mehri Khoshhali, Motahar Heidari‐Beni, Parnian Poursafa, Roya Kelishadi
Abstract
Epigenetic modifications might be associated with serum triglycerides (TG) levels. This study aims to systematically review the studies on the relationship between the methylation of specific cytosine-phosphate-guanine (CpG) sites and serum TG levels. This systematic review and meta-analysis study was conducted according to the PRISMA 2020 (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement. A systematic literature search was conducted in Medline database (PubMed), Scopus, and Cochrane library up to end of 2020. All observational studies (cross-sectional, case-control, [...]
Topics & Concepts
DNA methylationMedicineEpigeneticsMethylationMeta-analysisSystematic reviewInternal medicineCpG siteCochrane LibraryBiomarkerEndocrinologyBioinformaticsMEDLINEOncologyGeneGeneticsBiologyBiochemistryGene expressionEpigenetics and DNA MethylationCancer-related gene regulationRNA modifications and cancer