Synthesis of carbon dot based Schiff bases and selective anticancer activity in glioma cells
Yafeng Zhuang, Liping Zhu, Xiaoping Chen, Jing Chen, Zhoujie Ye, Jie Kang, Xinrui Wang, Zhizhong Han
Abstract
, resulted in approximately 13 times higher intracellular ROS production than in the control group. These experiments offer evidence that CDSBs induce mitochondrial damage, leading to a reduction in mitochondrial membrane potential in GL261 cells. In particular, in this work, CDs serve not as carriers, but as an integral part of the anticancer drugs, which can expand the role of CDs in cancer treatment.
Topics & Concepts
Schiff baseChemistryGliomaCombinatorial chemistryCarbon fibersStereochemistryCancer researchMaterials scienceBiologyComposite numberComposite materialCarbon and Quantum Dots ApplicationsSynthesis and Biological EvaluationOrganoselenium and organotellurium chemistry