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Proximity between LAG-3 and the T cell receptor guides suppression of T cell activation and autoimmunity

Jasper Du, H. Chen, Jia You, Wei Hu, Jia Liu, Lu Qiao, Yong Zhang, Jie Gao, Meng‐Ju Lin, Connor Foster, Eric Rao, Michael Cammer, Weiwei Yin, Shohei Koide, Ping Lu, Wei Chen, Jizhong Lou, Jun Wang

2025Cell26 citationsDOI

Topics & Concepts

BiologyT-cell receptorCD8Major histocompatibility complexMHC class ICell biologyT cellAutoimmunityCytotoxic T cellMHC class IIReceptorImmunologyImmune systemCancer researchGeneticsIn vitroCancer Immunotherapy and BiomarkersCAR-T cell therapy researchImmune Cell Function and Interaction
Proximity between LAG-3 and the T cell receptor guides suppression of T cell activation and autoimmunity | Litcius