Protective role of ACE2 and its downregulation in SARS-CoV-2 infection leading to Macrophage Activation Syndrome: Therapeutic implications
Nehla Banu, Sandeep Surendra Panikar, Lizbeth Riera Leal, Annie Riera Leal
Topics & Concepts
Downregulation and upregulationCytokine stormAngiotensin-converting enzyme 2Macrophage activation syndromeCoronavirusInflammationReceptorImmunologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)MacrophageCoronavirus disease 2019 (COVID-19)Angiotensin IIBiologyVirologyMedicineDiseaseInternal medicineInfectious disease (medical specialty)GeneGeneticsIn vitroArthritisCOVID-19 Clinical Research StudiesPhagocytosis and Immune RegulationApelin-related biomedical research