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Polysubstituted pyrrolidines linked to 1,2,3-triazoles: Synthesis, crystal structure, DFT studies, acid dissociation constant, drug-likeness, and anti-proliferative activity

Tuncay İnce, Rıza Serttas, Bünyamin Demır, Hasan Atabey, Nurgül Seferoğlu, Suat Erdoğan, Ertan Şahi̇n, Selma Erat, Yahya Nural

2020Journal of Molecular Structure40 citationsDOI

Topics & Concepts

ChemistryDissociation constantDensity functional theoryCrystal structureProton NMRTitrationPotentiometric titrationCrystallographyStereochemistryMedicinal chemistryComputational chemistryPhysical chemistryElectrodeBiochemistryReceptorSynthesis and biological activityClick Chemistry and ApplicationsSynthesis and Characterization of Heterocyclic Compounds
Polysubstituted pyrrolidines linked to 1,2,3-triazoles: Synthesis, crystal structure, DFT studies, acid dissociation constant, drug-likeness, and anti-proliferative activity | Litcius