Toward a Universal Definition of Etiologies in Heart Failure: Categorizing Causes and Advancing Registry Science
Anubha Agarwal, Jasper Tromp, Wael Almahmeed, Christiane E. Angermann, Chanchal Chandramouli, Hyun‐Jai Cho, Dong‐Ju Choi, Albertino Damasceno, Gerasimos Filippatos, Gregg C. Fonarow, S Harikrishnan, Lars H. Lund, Fred Masoudi, George A. Mensah, Asad Pathan, Pablo Perel, Fausto J. Pinto, Antônio Luiz Pinho Ribeiro, Stuart Rich, Yasuhiko Sakata, Karen Sliwa, Johan Sundström, Renee Wong, Clyde W. Yancy, Kelvin Yiu, Jian Zhang, Yuhui Zhang, Carolyn S.P. Lam, Gregory A. Roth, The Global Heart Failure Roundtable Group
Abstract
Heart failure (HF) is a well-described final common pathway for a broad range of diseases however substantial confusion exists regarding how to describe, study, and track these underlying etiologic conditions. We describe (1) the overlap in HF etiologies, comorbidities, and case definitions as currently used in HF registries led or managed by members of the global HF roundtable; (2) strategies to improve the quality of evidence on etiologies and modifiable risk factors of HF in registries; and (3) opportunities to use clinical HF registries as a platform for public health surveillance, implementation research, and randomized registry trials to reduce the global burden of noncommunicable diseases. Investment and collaboration among countries to improve the quality of evidence in global HF registries could contribute to achieving global health targets to reduce noncommunicable diseases and overall improvements in population health.