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Wavelength-Selective Activation of Photocaged DNAzymes for Metal Ion Sensing in Live Cells

Xiao Xu, Xiao Lu, Chunmei Gu, Jiachen Shang, Yu Xiang

2021ACS Omega21 citationsDOIOpen Access PDF

Abstract

-dependent DNAzyme sensor as a model, we achieved wavelength-selective activation of photocaged DNAzymes in live human cells by UV and visible light, laying the groundwork for the logic activation of DNAzyme-based sensors in biological systems.

Topics & Concepts

DeoxyribozymeNanotechnologyMetal ions in aqueous solutionChemistryBiosensorIonMaterials scienceDNAOptoelectronicsBiochemistryOrganic chemistryAdvanced biosensing and bioanalysis techniquesBiosensors and Analytical DetectionMolecular Sensors and Ion Detection
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