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Long-Acting Injectable HIV Therapy Outcomes Among Persons With HIV Who Have Adherence Challenges to Oral Antiretroviral Therapy

Elizabeth Hastie, Lucas Hill, Laura Bamford, Afsana Karim, Thomas Martin

2025Clinical Infectious Diseases14 citationsDOIOpen Access PDF

Abstract

Long-acting injectable cabotegravir/rilpivirine (LAI-CAB/RPV) may improve outcomes among persons with human immunodeficiency virus (PWH) with adherence difficulties to oral therapy. In this real-world observational study, over 85% of PWH remained on therapy and virally suppressed 48 weeks after initiating LAI-CAB/RPV. Providers should consider LAI therapy among PWH with adherence difficulties.

Topics & Concepts

MedicineRilpivirineAntiretroviral therapyObservational studyHuman immunodeficiency virus (HIV)Medication adherenceIntensive care medicineViral loadInternal medicineFamily medicineHIV/AIDS Research and InterventionsHIV Research and TreatmentHIV/AIDS drug development and treatment
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