Improvement of obesity by Liupao tea is through the IRS-1/PI3K/AKT/GLUT4 signaling pathway according to network pharmacology and experimental verification
Zhimin Wu, Wenxin Yu, Wei‐Ju Ni, Cuiqin Teng, Weile Ye, Cuiping Yu, Yu Zeng
Topics & Concepts
PI3K/AKT/mTOR pathwayProtein kinase BInsulin receptorGLUT4ChemistryFatty acid synthaseBiochemistryEpigallocatechin gallateAdipogenesisSignal transductionInsulin resistancePharmacologyBiologyFatty acidInsulinIn vitroEndocrinologyPolyphenolAntioxidantTea Polyphenols and EffectsSirtuins and Resveratrol in MedicinePhytochemicals and Antioxidant Activities