Synthesis of Polycyclic Natural Products through Skeletal Rearrangement
Satoshi Yokoshima
Abstract
Construction of rings through reliable reactions followed by changes in the ring size or the connectivity through skeletal rearrangement provides molecules with a wide range of skeletons. In this account, our syntheses of polycyclic natural products through skeletal rearrangement are discussed. 1 Introduction 2 Synthesis through Changes in the Ring Size 3 Synthesis by Biomimetic Strategies 4 Synthesis through Metathesis 5 Synthesis through Temporary Formation of a Ring 6 Conclusion
Topics & Concepts
ChemistryRing (chemistry)Ring sizeCope rearrangementMetathesisRearrangement reactionSalt metathesis reactionTotal synthesisStereochemistryCombinatorial chemistryOrganic chemistryCatalysisPolymerizationPolymerSynthetic Organic Chemistry MethodsChemical synthesis and alkaloidsMarine Sponges and Natural Products