Expediting online liquid chromatography for real-time monitoring of product attributes to advance process analytical technology in downstream processing of biopharmaceuticals
Tobias Graf, Lukas Naumann, Lea Bonnington, Jakob Heckel, Bernhard Spensberger, Sascha Klein, Christoph Brey, Ronnie Nachtigall, Maximilian Mroz, Thomas Vagn Hogg, Christopher McHardy, Andrés Martínez, Reinhard Braaz, Michael Leiß
Topics & Concepts
ExpeditingProcess analytical technologyDownstream (manufacturing)BiopharmaceuticalDownstream processingQuality (philosophy)Quality by DesignProduct (mathematics)Process (computing)ExpansiveProcess engineeringBiochemical engineeringComputer scienceSensitivity (control systems)Critical quality attributesChemistryChromatographyWork in processSystems engineeringEngineeringOperations managementMathematicsGeneticsCompressive strengthGeometryEpistemologyElectronic engineeringOperating systemMaterials scienceBiologyComposite materialPhilosophyViral Infectious Diseases and Gene Expression in InsectsProtein purification and stabilityInnovative Microfluidic and Catalytic Techniques Innovation