Understanding the effect of increased cell specific productivity on galactosylation of monoclonal antibodies produced using Chinese hamster ovary cells
Sri Ranganayaki Madabhushi, Alexei A. Podtelezhnikov, Nicholas Murgolo, Sen Xu, Henry Lin
Topics & Concepts
Chinese hamster ovary cellSodium butyrateDownregulation and upregulationMonoclonal antibodyChemistryGlycosylationButyrateCell cultureTransporterGlycanCell biologyBiochemistryAntibodyGlycoproteinBiologyGeneImmunologyGeneticsFermentationReceptorViral Infectious Diseases and Gene Expression in InsectsProtein purification and stabilityMonoclonal and Polyclonal Antibodies Research