Potent ClpP agonists with anticancer properties bind with improved structural complementarity and alter the mitochondrial N-terminome
Mark Mabanglo, Keith S. Wong, Marim Barghash, Elisa Leung, Stephanie H. W. Chuang, Afshan Ardalan, Emily Majaesic, Cassandra J. Wong, Shen Zhang, Henk Lang, Donald S. Karanewsky, Andrew A. Iwanowicz, Lee M. Graves, Edwin J. Iwanowicz, Anne‐Claude Gingras, Walid A. Houry
Topics & Concepts
Cancer cellBiochemistryCell biologyChemistryProteasesReactive oxygen speciesCarcinogenesisBiologyEnzymeCancerGeneticsGeneMitochondrial Function and PathologyATP Synthase and ATPases ResearchRNA and protein synthesis mechanisms