Health equality, race and pharmacogenomics
Emma Magavern, Deepti Gurdasani, Fu Liang Ng, Sandra Soo‐Jin Lee
Abstract
Pharmacogenomics is increasingly moving into mainstream clinical practice. Careful consideration must be paid to inclusion of diverse populations in research, translation and implementation, in the historical and social context of population stratification, to ensure that this leads to improvements in healthcare for all rather than increased health disparities. This review takes a broad and critical approach to the current role of diversity in pharmacogenomics and addresses potential pitfalls in order to raise awareness for prescribers. It also emphasizes evidence gaps and suggests approaches that may minimize negative consequences and promote health equality.
Topics & Concepts
PharmacogenomicsMainstreamRace (biology)Health equityContext (archaeology)Health careInclusion (mineral)Race and healthPopulation healthMedicinePopulationPublic healthSociologyPolitical scienceSocial scienceBiologyNursingEnvironmental healthPharmacologyPaleontologyGender studiesLawPharmacogenetics and Drug MetabolismGenetic Associations and EpidemiologyGenomics and Rare Diseases