3D printing nacre powder/sodium alginate scaffold loaded with PRF promotes bone tissue repair and regeneration
Bin Liu, Cewen Hu, Xinyue Huang, Kaiqi Qin, Lei Wang, Zhilong Wang, Jiachen Liang, Fuqiang Xie, Zengjie Fan
Abstract
. Then, platelet-rich fibrin (PRF), containing a mass of growth factors, was loaded on the NP/SA scaffolds. This was aimed to fully maximize the synergistic effect with NP, thereby accelerating bone tissue regeneration. Overall, this study marks the first instance of preparing a bionic bone structure scaffold containing NP by 3D printing technology, which is combined with PRF to further accelerate bone regeneration. These findings offer a new treatment strategy for bone tissue regeneration in clinical applications.
Topics & Concepts
ScaffoldRegeneration (biology)Sodium alginateChemistryBiocompatible materialBiomedical engineeringBone healingSodiumAnatomyCell biologyMedicineBiologyOrganic chemistryBone Tissue Engineering Materials3D Printing in Biomedical ResearchAdditive Manufacturing and 3D Printing Technologies