Biogenesis of secretory immunoglobulin M requires intermediate non‐native disulfide bonds and engagement of the protein disulfide isomerase ERp44
Chiara Giannone, Maria Rita Chelazzi, Andrea Orsi, Tiziana Anelli, Tuan Nguyen, Johannes Büchner, Roberto Sitia
Topics & Concepts
Protein disulfide-isomeraseBiologyBiogenesisDisulfide bondIsomeraseAntibodyBiochemistryCell biologyEnzymeGeneticsGeneEndoplasmic Reticulum Stress and DiseaseTransgenic Plants and ApplicationsPancreatic function and diabetes