Synthesis of <i>gem</i>-di(boryl)cyclopropanes from non-activated olefins <i>via</i> Mn-photocatalyzed atom transfer radical addition
Jiefeng Hu, Kun Zhang, Jing Wang, Mingming Huang, Shuangru Chen, Zhuangzhi Shi, Todd B. Marder
Abstract
an intermolecular halogen-atom transfer radical addition, followed by deprotonative alkylation with lithium diisopropylamide, ultimately yielding cyclization products. The versatility and practicality of this approach are further highlighted by the successful implementation of several transformations, which provide an expedited route for synthesizing highly functionalized molecules.
Topics & Concepts
ChemistryMedicinal chemistryAtom-transfer radical-polymerizationAtom (system on chip)PhotochemistryOrganic chemistryPolymerizationEmbedded systemPolymerComputer scienceRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsOrganoboron and organosilicon chemistry