BF<sub>3</sub>·OEt<sub>2</sub> catalyzed synthesis of functionalized 9-fluorene-9-ylidene appended quinazolin-4-ones
Mohanakumaran Athira, Suresh Snoxma Smile, Ponnusamy Shanmugam
Abstract
An efficient method for the construction of the quinazolinone skeleton from the reaction of 9-(phenylethynyl)-9 H -fluoren-9-ols with substituted 2-aminobenzamides catalyzed by boron trifluoride is achieved.
Topics & Concepts
ChemistryFluoreneCatalysisCombinatorial chemistryMedicinal chemistryStereochemistryOrganic chemistryPolymerQuinazolinone synthesis and applicationsAdvanced Synthetic Organic ChemistrySynthesis and Biological Evaluation