Probiotics induce intestinal IgA secretion in weanling mice potentially through promoting intestinal APRIL expression and modulating the gut microbiota composition
Maozhen Zhao, Xi Liang, Meng Yang, Haiyan Lü, Kai Lin, Pimin Gong, Tongjie Liu, Huaxi Yi, Jiancun Pan, Yongjiu Zhang, Zhe Zhang, Lanwei Zhang
Abstract
FL276.1 can induce IgA production in the intestinal tract of weanling mice by promoting intestinal APRIL expression and mediating changes in the gut microbiota, thus playing a significant role in enhancing local intestinal immunity in infants.
Topics & Concepts
WeanlingSecretionGut floraBiologyComposition (language)Secretory IgAImmunologyMicrobiologyImmune systemEndocrinologyPhilosophyLinguisticsGut microbiota and healthGastrointestinal motility and disordersInfant Nutrition and Health