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Physical fitness and activity level in Norwegian adults with achondroplasia

Olga Marieke de Vries, Heidi Johansen, Svein O. Fredwall

2020American Journal of Medical Genetics Part A23 citationsDOIOpen Access PDF

Abstract

Abstract This cross‐sectional Physical Fitness Study compared cardiorespiratory fitness (VO 2 peak), six‐minute walk test (6MWT), muscle strength (30sSTS), balance (BESS), and self‐reported physical activity level (IPAQ) in Norwegian adults with achondroplasia (ACH) to reference values of average‐statured individuals. The feasibility of the physical fitness tests and IPAQ was explored. Forty‐three adults (22 women) participated. Mean age was 38 years (range 16–69 years). Mean differences (95% CI) for men and women with ACH compared to reference values were: VO 2 peak. −7.0 m/min/kg (−13.6 to −0.5, p = .037), and − 7.9 ml/kg/min (−11.6 to −4.3, p < .001); 6MWT −270.8 m (−340.4 to −201.2, p < .001), and − 196.7 m (−244.3 to −149.0, p = .001); 30sSTS ‐4.6 repetitions (−7.8 to −1.5, p = .006), and − 1.1 repetitions (−3.4 to 1.1, p = .335). There were no differences within ACH participants, except for VO 2 peak, where men performed better. Sufficient physical activity (> 600 metabolic equivalent of task weekly) was achieved by 79% of the participants. The feasibility of the 6MWT and 30sSTS was good. There was a strong correlation between the VO 2 peak and 6MWT (men: r = 0.63, p = .007; women: r = 0.71, p < .001). The findings indicate that the 6MWT and 30sSTS test are useful in assessing functional exercise capacity and muscle strength in adults with ACH.

Topics & Concepts

Cardiorespiratory fitnessAchondroplasiaMedicinePhysical fitnessBalance (ability)Physical activityPhysical therapyInternal medicineNorwegianPediatricsPhilosophyLinguisticsCardiovascular Function and Risk FactorsAdipose Tissue and MetabolismConnective tissue disorders research
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