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Contribution of heterozygous PCSK1 variants to obesity and implications for precision medicine: a case-control study

Lise Folon, Morgane Baron, Bénédicte Toussaint, Emmanuel Vaillant, Mathilde Boissel, Victoria Scherrer, Hélène Loiselle, Audrey Leloire, Alaa Badreddine, Beverley Balkau, G. Charpentier, Sylvia Franc, Michel Marre, Soulaimane Aboulouard, Michel Salzet, Mickaël Canouil, Mehdi Derhourhi, Philippe Froguel, Amélie Bonnefond

2023The Lancet Diabetes & Endocrinology32 citationsDOIOpen Access PDF

Topics & Concepts

MedicineMissense mutationOverweightObesityCompound heterozygosityInternal medicineHNF1ACohortType 2 diabetesDiabetes mellitusEndocrinologyGeneticsGeneAlleleMutationBiologyLipoproteins and Cardiovascular HealthProtease and Inhibitor MechanismsGenomics and Rare Diseases
Contribution of heterozygous PCSK1 variants to obesity and implications for precision medicine: a case-control study | Litcius